Welcome to REVIVE

Advancing care to save lives affected by Advanced HIV Disease

REVIVE is a clinical trial dedicated to reducing mortality and improving care for people with Advanced HIV Disease (AHD).

AHD is a leading cause of death in sub-Saharan Africa and presents significant public health challenges. Severe bacterial infections, which often occur during the critical early period after starting antiretroviral therapy, are a major driver of mortality in people with AHD.

Through innovative research, the REVIVE trial aims to provide the evidence needed to support the use of azithromycin prophylaxis as part of routine HIV care. By tackling a critical cause of early mortality, we aim to save lives and deliver better outcomes for people living with AHD.

Learn more about the trial
Welcome to REVIVE

REVIVE in numbers

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Total participants randomised

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Countries involved

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Active clinical sites

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Recent randomisations (last 30 days)

Last updated date

2026-08-19

Stay informed with REVIVE webinars and events

Investigators Meeting

Investigators Meeting

Date: 2 September 2026

Time: 08:00 SAT

Details: 2 September - 5 September 2026

Note: Location: Nairobi, Kenya

“New interventions that are affordable and safe are urgently needed to reduce the high mortality among people with advanced HIV disease. A successful REVIVE trial will provide definitive evidence for the use of azithromycin prophylaxis in this vulnerable population, saving lives in Africa and beyond.”

Dr Sean Wasserman, Principal Investigator at REVIVE

Proud partnership by leaders in global health.

Population Health Research Institute Logo
University of Cape Town Logo
Gates Foundation Logo

The REVIVE Clinical Trial is proudly funded by the Bill & Melinda Gates Foundation, driving innovation and impact in global health research.