Standard of care in advanced HIV disease: review of HIV treatment guidelines in sub-Saharan African countries—an extension study of eight countries
Topic: This article adds to a previous review by comparing eight additional countries' national AHD management guidelines to the 2021 WHO recommendations.
Standard of care in advanced HIV disease: review of HIV treatment guidelines in six sub-Saharan African countries
Topic: This article details national guidelines for the management of advanced HIV disease in six sub-Saharan African countries to assess their alignment with the 2021 WHO recommendations.
One-year mortality among adults with advanced HIV in sub-Saharan Africa: a systematic review and meta-analysis
Topic: In sub-Saharan Africa (SSA), people with HIV continue to present with advanced HIV disease (AHD), putting them at high risk of life-threatening opportunistic diseases. We aimed to estimate mortality among this population.
Resolving the CD4-testing crisis to help end AIDS-related deaths
Topic: This review highlights the importance of CD4 testing in diagnosing and managing advanced HIV disease, emphasising the decline in CD4 access and the need for sustainable solutions to address this.
Ending AIDS deaths requires improvements in clinical care for people with advanced HIV disease who are seriously ill
Topic: This article addresses the global challenge of managing advanced HIV disease, emphasising the distinct care needs of two patient groups: those at high risk of developing severe illness and those who are already severely ill.
Azithromycin to Reduce Childhood Mortality in Sub-Saharan Africa
Topic: The MORDOR trial examined the impact of mass azithromycin administration on reducing mortality among preschool children in sub-Saharan Africa.
Enhanced Prophylaxis plus Antiretroviral Therapy for Advanced HIV Infection in Africa
Topic: The REALITY trial investigated the effects of enhanced antimicrobial prophylaxis (including azithromycin) versus standard prophylaxis in people with advanced HIV disease.